Utilization of Prognostic Indexes for Patients with Brain Metastases in Daily Radiotherapy Routine - is the Complexity and Intricacy Still an Issue?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00063385" target="_blank" >RIV/00159816:_____/15:00063385 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/15:#0000711

Result on the web

<a href="http://dx.doi.org/10.14735/amko2015352" target="_blank" >http://dx.doi.org/10.14735/amko2015352</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amko2015352" target="_blank" >10.14735/amko2015352</a>

Result language

angličtina

Original language name

Utilization of Prognostic Indexes for Patients with Brain Metastases in Daily Radiotherapy Routine - is the Complexity and Intricacy Still an Issue?

Original language description

Many prognostic indexes are available for patients with brain metastases in order to estimate remaining lifetime before selection of appropriate treatment including palliative radiotherapy. Their routine utilization is often deprecated for their complexity. We developed a practical tool based on widely available spreadsheet editors for facilitation of daily clinical use of selected indexes (RPA, GPA and WBRT- 30) and evaluated its usage for retrospective single institutional survival analysis of patients irradiated for brain metastases. Patients and Methods: Spreadsheet platform was prepared and adjusted for automatic calculation of selected prognostic indexes after input of the relevant parameters. The consecutive series of newly diagnosed patients referred during 2011 to the palliative brain radiotherapy were analyzed, and real calculated survival parameters of individual subgroups of RPA, GPA and WBRT- 30 were compared with estimated ones. Correlation of radiotherapy technique and estimated survival at the time of treatment indication was evaluated. Results: Total of 121 patients (61% with multiple metastases) were irradiated with the majority undergoing whole brain radiotherapy. Median overall survival from the time of radiotherapy indication was 3.13 months. Non- balanced distribution into individual scoring systems subgroups was observed with 8 (7%), 89 (73%) and 24 (20%) patients assigned to RPA 1, 2 and 3 subgroup, 3 (3%), 9 (7%), 57 (47%) and 52 (43%) patients assigned to GPA 3.5- 4, GPA 3.0, GPA 1.5- 2.5 and GPA 0- 1.0 subgroup and 10 (8%), 88 (73%) and 23 (19%) patients assigned to WBRT- 30 subgroup D, B and A. Entire differences in overall survival between subgroups are significant among all three scoring systems.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Klinická onkologie

ISSN

0862-495X

e-ISSN

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Volume of the periodical

28

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

352-358

UT code for WoS article

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EID of the result in the Scopus database

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