Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069228" target="_blank" >RIV/00159816:_____/18:00069228 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/18:00106956

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Correlation between transversal and orthogonal maximal diameters of abdominal aortic aneurysms and alternative rupture risk predictors

Original language description

There is no standard for measuring maximal diameter (Dmax) of abdominal aortic aneurysm (AAA) from computer tomography (CT) images although differences between Dmax evaluated from transversal (axialDmax) or orthogonal (orthoDmax) planes can be large especially for angulated AAAs. Therefore we investigated their correlations with alternative rupture risk indicators as peak wall stress (PWS) and peak wall rupture risk (PWRR) to decide which Dmax is more relevant in AAA rupture risk assessment. Material and methods: The Dmax values were measured by a trained radiologist from 70 collected CT scans, and the corresponding PWS and PWRR were evaluated using Finite Element Analysis (FEA). The cohort was ordered according to the difference between axialDmax and orthoDmax (Da-o) quantifying the aneurysm angulation, and Spearman&apos;s correlation coefficients between PWS/PWRR - orthoDmax/axialDmax were calculated. Part of the patients took part in a Grant of the Ministry of Health of the Czech Republic (no. 17-29701A). Results: The calculated correlations PWS/PWRR vs. orthoDmax were substantially higher for angulated AAAs (with Da-o &gt;=3mm). Under this limit, the correlations were almost the same for both Dmax values. Analysis of AAAs divided into two groups of angulated (n=38) and straight (n=32) cases revealed that both groups are similar in all parameters (orthoDmax, PWS, PWRR) with the exception of axialDmax (p=0.024). Conclusions: It was confirmed that orthoDmax is better correlated with the alternative rupture risk predictors PWS and PWRR for angulated AAAs (Da-o &gt;=3mm) while there is no difference between orthoDmax and axialDmax for straight AAAs (Da-o &lt;3mm). As angulated AAAs represent a significant portion of cases it can be recommended to use orthoDmax as the only Dmax parameter for AAA rupture risk assessment.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

30212 - Surgery

Project

<a href="/en/project/NV17-29701A" target="_blank" >NV17-29701A: Ischemia modified albumin and circulating microRNAs as a new technology for monitoring of tissue ischemia following abdominal aortic vascular surgery</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů