Poor ventilatory efficiency during exercise may predict prolonged air leak after pulmonary lobectomy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00071916" target="_blank" >RIV/00159816:_____/20:00071916 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/20:00115432 RIV/65269705:_____/20:00071916

Result on the web

<a href="https://academic.oup.com/icvts/advance-article/doi/10.1093/icvts/ivz255/5599861" target="_blank" >https://academic.oup.com/icvts/advance-article/doi/10.1093/icvts/ivz255/5599861</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/icvts/ivz255" target="_blank" >10.1093/icvts/ivz255</a>

Result language

angličtina

Original language name

Poor ventilatory efficiency during exercise may predict prolonged air leak after pulmonary lobectomy

Original language description

Poor ventilatory efficiency, defined as the increase in minute ventilation relative to carbon dioxide production during exercise (VE/VCO2 slope), may be associated with dynamic hyperinflation and thereby promote the development of prolonged air leak (PAL) after lung resection. Consecutive lung lobectomy candidates (n = 96) were recruited for this prospective two-centre study. All subjects underwent pulmonary function tests and cardiopulmonary exercise testing prior to surgery. PAL was defined as the presence of air leaks from the chest tube on the 5th postoperative day and developed in 28 (29%) subjects. Subjects with PAL were not different in terms of age, sex, American Society of Anesthesiologists class, type of surgery (thoracotomy/video-assisted thoracoscopic surgery) and site of surgery (right/left lung; upper/lower lobes). Subjects with PAL had more frequent pleural adhesions (50% vs 21%; P = 0.006) and steeper VE/VCO2 slope (35 +- 7 vs 30 +- 5; P = 0.001). Stepwise logistic regression showed that only the presence of pleural adhesions [odds ratio (OR) 3.9, 95% confidence interval (CI) 1.4-10.9; P = 0.008] and VE/VCO2 slope (OR 1.1, 95% CI 1.0-1.2; P = 0.003) were independently associated with PAL (AUC 0.74, 95% CI 0.62-0.86). We conclude that a high VE/VCO2 slope during exercise may be helpful in identifying patients at greater risk for the development of PAL after lung lobectomy. Clinical trial registration number: ClinicalTrials.gov identifier: NCT03498352.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30203 - Respiratory systems

Project

<a href="/en/project/NV18-06-00216" target="_blank" >NV18-06-00216: Rest Ventilatory Parameters Predict Morbidity and Mortality in Patients Undergoing Thoracic Surgery</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Interactive cardiovascular and thoracic surgery

ISSN

1569-9293

e-ISSN

—

Volume of the periodical

30

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

4

Pages from-to

269-272

UT code for WoS article

000517789800011

EID of the result in the Scopus database

2-s2.0-85079017748