The therapeutic effect of B-type natriuretic peptides in acute decompensated heart failure
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00073078" target="_blank" >RIV/00159816:_____/20:00073078 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1111/1440-1681.13290" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1111/1440-1681.13290</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/1440-1681.13290" target="_blank" >10.1111/1440-1681.13290</a>
Alternative languages
Result language
angličtina
Original language name
The therapeutic effect of B-type natriuretic peptides in acute decompensated heart failure
Original language description
B-type natriuretic peptide (BNP) exhibits roles in natriuresis and diuresis, making it an ideal drug that may aid in diuresing a fluid-overloaded patient with poor or worsening renal function. Several randomized clinical trials have tested the hypothesis that infusions of pharmacological doses of BNP to acute heart failure (HF) patients may enhance decongestion and preserve renal function in this clinical setting. Unfortunately, none of these have demonstrated beneficial outcomes. The current challenge for BNP research in acute HF lies in addressing a failure of concept and a reluctance to abandon an ineffective research model. Future success will necessitate a detailed understanding of the mechanism of action of BNP, as well as better integration of basic and clinical science.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30104 - Pharmacology and pharmacy
Result continuities
Project
<a href="/en/project/GA18-13663S" target="_blank" >GA18-13663S: COMPUTATIONAL MODELLING OF RUPTURE RISK OF ATHEROSCLEROTIC PLAQUES IN CAROTID ARTERIES</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical and Experimental Pharmacology and Physiology
ISSN
1440-1681
e-ISSN
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Volume of the periodical
47
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
1120-1133
UT code for WoS article
000520715900001
EID of the result in the Scopus database
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