Memory retrieval in temporal lobe epilepsy is related to functional segregation of the mesiotemporal structures

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00074662" target="_blank" >RIV/00159816:_____/21:00074662 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/21:00120192
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S1525505021004571?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S1525505021004571?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.yebeh.2021.108196" target="_blank" >10.1016/j.yebeh.2021.108196</a>

Result language
angličtina
Original language name
Memory retrieval in temporal lobe epilepsy is related to functional segregation of the mesiotemporal structures
Original language description
Objective: We analyzed the impact of temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS) on functional connectivity (FC) between mesiotemporal structures. Functional connectivity modifications related to word retrieval were investigated. Methods: High-density EEG of 21 patients with TLE with HS (12 left TLE and 9 right TLE) and 10 healthy controls (HCs) were recorded during a verbal subsequent memory paradigm. Electroencephalography data were reconstructed into the source space and FC was calculated from the source activity of regions of interest. Results: A significant decrease in FC between the right-and left-sided mesiotemporal structures in TLE was observed. The decrease was significant only with words that were correctly recognized. The decrease in interhemispheric FC between mesiotemporal structures was found in the 8-to 20-Hz frequency range in both left and right TLE. Significance: The decreased FC between the mesiotemporal structures in TLE is a condition for successful performance of a memory retrieval task. The successful memory retrieval in TLE is related to functional segregation of lesional from nonlesional mesiotemporal structures. This decrease was absent in non successful responses. (c) 2021 Elsevier Inc. All rights reserved.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology

Project
<a href="/en/project/NU21-04-00254" target="_blank" >NU21-04-00254: Detection of seizure onset zone in multi-lesional epilepsies using multimodal imaging methods</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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