Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F21%3A00075129" target="_blank" >RIV/00159816:_____/21:00075129 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/21:00120174
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.scr.2021.102378" target="_blank" >10.1016/j.scr.2021.102378</a>
Alternative languages
Result language
angličtina
Original language name
Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls
Original language description
Human induced pluripotent stem cell (iPSC) lines were generated from patients with spontaneous late-onset Alzheimer's disease (AD) and three healthy control individuals. Peripheral blood mononuclear cells were reprogrammed with Yamanaka factors (OSKM) using a commercially available Epi5 Reprogramming Kit. The pluripotency of iPSCs was confirmed by the expression of pluripotency factors and by their ability to differentiate to all three germ layers in vitro. Newly derived cell lines can be used to model Alzheimer's disease in vitro.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
<a href="/en/project/NV19-08-00472" target="_blank" >NV19-08-00472: Clinically relevant biochemical, immunological and cellular biomarkers of Alzheimer's disease and aging</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Stem Cell Research
ISSN
1873-5061
e-ISSN
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Volume of the periodical
53
Issue of the periodical within the volume
May
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
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UT code for WoS article
000656247000002
EID of the result in the Scopus database
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