Short-term effects of transcranial direct current stimulation on motor speech in Parkinson's disease: a pilot study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F24%3A00080561" target="_blank" >RIV/00159816:_____/24:00080561 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/24:00136520 RIV/00216305:26220/24:PU151244

Result on the web

<a href="https://link.springer.com/article/10.1007/s00702-024-02771-5" target="_blank" >https://link.springer.com/article/10.1007/s00702-024-02771-5</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-024-02771-5" target="_blank" >10.1007/s00702-024-02771-5</a>

Result language

angličtina

Original language name

Short-term effects of transcranial direct current stimulation on motor speech in Parkinson's disease: a pilot study

Original language description

Introduction: Hypokinetic dysarthria (HD) is a common motor speech symptom of Parkinson&apos;s disease (PD) which does not respond well to PD treatments. We investigated short-term effects of transcranial direct current stimulation (tDCS) on HD in PD using acoustic analysis of speech. Based on our previous studies we focused on stimulation of the right superior temporal gyrus (STG) - an auditory feedback area. Methods: In 14 PD patients with HD, we applied anodal, cathodal and sham tDCS to the right STG using a cross-over design. A protocol consisting of speech tasks was performed prior to and immediately after each stimulation session. Linear mixed models were used for the evaluation of the effects of each stimulation condition on the relative change of acoustic parameters. We also performed a simulation of the mean electric field induced by tDCS. Results: Linear mixed model showed a statistically significant effect of the stimulation condition on the relative change of median duration of silences longer than 50 ms (p = 0.015). The relative change after the anodal stimulation (mean = -5.9) was significantly lower as compared to the relative change after the sham stimulation (mean = 12.8), p = 0.014. We also found a correlation between the mean electric field magnitude in the right STG and improvement of articulation precision after anodal tDCS (R = 0.637; p = 0.019). Conclusions: The exploratory study showed that anodal tDCS applied over the auditory feedback area may lead to shorter pauses in a speech of PD patients.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

1435-1463

Volume of the periodical

131

Issue of the periodical within the volume

7

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

791-797

UT code for WoS article

001199193000001

EID of the result in the Scopus database

—