Paradoxes and Pitfalls of Interleukin-33 in Atherosclerosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10123801" target="_blank" >RIV/00179906:_____/12:10123801 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/12:10123801
Result on the web
<a href="http://www.benthamscience.com/open/tocchemj/" target="_blank" >http://www.benthamscience.com/open/tocchemj/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/1874241601205010013" target="_blank" >10.2174/1874241601205010013</a>
Alternative languages
Result language
angličtina
Original language name
Paradoxes and Pitfalls of Interleukin-33 in Atherosclerosis
Original language description
Atherosclerosis is definitely considered as an inflammatory/immunopathological disease. The long-standing low-grade inflammation is focused on the components of the vessel wall. Initially, this inflammation was assumed to be driven by the pro-inflammatory Th1 cellular and cytokine immune responses. On the basis of accumulating knowledge, however, this view has been specified to include the Th17/Th1 axis which underlies most immunopathological diseases accompanied by sterile inflammation. On the other hand, an anti-inflammatory Th2 cellular and cytokine immune re-sponse attempts to dampen these unfavorable reactions which terminate in full-blown atherosclerosis. Interleukin-33, the novel member of the IL-1 cytokine superfamily, was suggested to take part in the anti-atherogenic response by mediating the Th1-to-Th2 switch of the immune reactions. However, IL-33 is a multifaceted mediator with both pro- and anti-inflammatory activities. IL-33 presents both an extracellular (cytokine-like)
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Open Clinical Chemistry Journal
ISSN
1874-2416
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
13-20
UT code for WoS article
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EID of the result in the Scopus database
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