Actual position of interleukin(IL)-33 in atherosclerosis and heart failure: Great Expectations or En attendant Godot?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F15%3A10297473" target="_blank" >RIV/00216208:11150/15:10297473 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/15:10297473

Result on the web

<a href="http://dx.doi.org/10.1177/0267659114562269" target="_blank" >http://dx.doi.org/10.1177/0267659114562269</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/0267659114562269" target="_blank" >10.1177/0267659114562269</a>

Result language

angličtina

Original language name

Actual position of interleukin(IL)-33 in atherosclerosis and heart failure: Great Expectations or En attendant Godot?

Original language description

Atherosclerosis has been recognized as an inflammatory/autoimmune disease. The long-standing low-grade inflammation which fuels its development is primarily focused on the components of the vessel wall. Originally, inflammation in atherogenesis was supposed to be driven by the pro-inflammatory Th1 cellular and cytokine immune response. On the basis of accumulating evidence, this view has been re-evaluated to include the Th17/Th1 axis which is shared by most diseases of sterile inflammation. The anti-inflammatory Th2 cellular and cytokine immune response is initiated concomitantly with the former two, the latter dampening their harmful reactions which culminate in full-blown atherosclerosis. Interleukin-33, a novel member of the IL-1 cytokine superfamily, was suggested to take part in the anti-atherogenic response by mediating the Th1-to-Th2 switch of the immune reactions. However, IL-33 is a multifaceted mediator with both pro- and anti-inflammatory activities, also called a dual facto

Czech name

—

Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Perfusion

ISSN

0267-6591

e-ISSN

—

Volume of the periodical

30

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

19

Pages from-to

356-374

UT code for WoS article

000356011400002

EID of the result in the Scopus database

2-s2.0-84930828813