Diagnostic performance of urinary metanephrines for the postmortem diagnosis of hypothermia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10284349" target="_blank" >RIV/00179906:_____/14:10284349 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10284349
Result on the web
<a href="http://dx.doi.org/10.1007/s12024-014-9585-0" target="_blank" >http://dx.doi.org/10.1007/s12024-014-9585-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s12024-014-9585-0" target="_blank" >10.1007/s12024-014-9585-0</a>
Alternative languages
Result language
angličtina
Original language name
Diagnostic performance of urinary metanephrines for the postmortem diagnosis of hypothermia
Original language description
The purpose of this study was to assess the diagnostic potential of urinary metanephrines and 3-methoxytyramine compared to urinary catecholamine determination in diagnosing antemortem cold exposure and fatal hypothermia. 83 cases of fatal hypothermia and 144 control cases were included in this study. Catecholamines (adrenaline, noradrenaline and dopamine), metanephrines (metanephrine, normetanephrine) and 3-methoxytyramine were measured in urine collected during autopsy. All tested analytes were significantly higher in hypothermia cases compared to control subjects and displayed a generally satisfying discriminative value, thus indicating urinary catecholamines and their metabolites as reliable markers of cold-related stress and hypothermia related-deaths. Metanephrine and adrenaline had the best discriminative value between hypothermia and control cases compared to other tested analytes, though with different sensitivity and specificity. These can therefore be considered the most sui
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Forensic Science, Medicine, and Pathology
ISSN
1547-769X
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
518-525
UT code for WoS article
000344874800007
EID of the result in the Scopus database
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