Systemic Inflammatory Response After Open, Laparoscopic and Robotic Surgery in Endometrial Cancer Patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10327985" target="_blank" >RIV/00179906:_____/16:10327985 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/16:73578717

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Systemic Inflammatory Response After Open, Laparoscopic and Robotic Surgery in Endometrial Cancer Patients

Original language description

Aim: To study inflammatory response and nutritional biomarkers in operated endometrial cancer (EC) patients. Materials and Methods: A total 109 consecutive EC patients undergoing open laparotomy (LT), laparoscopic (LS) or robot-assisted surgery (RS) were studied. Twenty four patients served as controls. Pre- and postoperative levels of inflammatory and nutritional biomarkers were analyzed prospectively. Results: The estimated blood loss was significantly lower in RS compared to all other groups. C-reactive protein (CRP) and interleukin-6 (IL-6) correlated with each other and exhibited positive correlation with age, body-mass index (BMI), leukocyte count, platelet count, kynurenine, kynurenine/tryptophan ratio and urinary neopterin and a negative correlation with vitamin D and retinol. Hemoglobin, retinol, alpha-tocopherol, vitamin D and citrulline concentrations decreased and inflammatory biomarkers increased after surgery to a different extent in LT, LS, RS and control groups. Conclusion: The present data demonstrate a differential response to surgical trauma in patients with endometrial carcinoma.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/NT13566" target="_blank" >NT13566: Tissue trauma and postoperative stress in patients with surgically treated early endometrial cancer stages</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

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Volume of the periodical

36

Issue of the periodical within the volume

6

Country of publishing house

GR - GREECE

Number of pages

14

Pages from-to

2909-2922

UT code for WoS article

000377464200035

EID of the result in the Scopus database

2-s2.0-84991737425