Systemic inflammatory response after open, laparoscopic and robotic surgery in endometrial cancer patients.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A73578717" target="_blank" >RIV/61989592:15110/16:73578717 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/16:10327985

Result on the web

<a href="http://ar.iiarjournals.org/content/36/6/2909.full.pdf+html" target="_blank" >http://ar.iiarjournals.org/content/36/6/2909.full.pdf+html</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Systemic inflammatory response after open, laparoscopic and robotic surgery in endometrial cancer patients.

Original language description

Aim: To study inflammatory response and nutritional biomarkers in operated endometrial cancer patients. Material and methods: A total 109 consecutive patients with diagnosed endometrial cancer, who undergone open (LT), laparoscopic (LS) or robot assisted (RS) surgery represented a study group. Twenty four patients constituted a control group. Pre, Peri, and postoperative levels of CRP, IL-6, citrulline, vitamine D, alpha tocopherol, retinol, kynurenine, tryptophan, urinary neopterin, patient´s age, body mass index (BMI), blood loss, drop in hemoglobin, white blood cell levels, platelet count, number of lymphonodes retrieved, and visual analogue scale (VAS) scores were analyzed prospectively. Results: The estimated blood loss was significantly lower in RS compared to all other groups. Significantly higher number of lymph nodes was sampled during RS compared to LT. CRP and IL-6 correlated with each other and exhibited positive correlation with age, BMI, leukocyte count, platelet count, kynurenine, kynurenine/tryptophan ratio and urinary neopterin and a negative correlation with vitamin D and retinol. Similar pattern of correlations was observed when AUC (area under curve) values of biomarkers were correlated in endometrial cancer patients and controls with the exception of a negative correlation being observed between CRP and citrulline in endometrial cancer patients. Conclusion: Present data demonstrate a differential response to surgical trauma in patients with endometrial carcinoma.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

30214 - Obstetrics and gynaecology

Project

<a href="/en/project/NT13566" target="_blank" >NT13566: Tissue trauma and postoperative stress in patients with surgically treated early endometrial cancer stages</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

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Volume of the periodical

36

Issue of the periodical within the volume

6

Country of publishing house

GR - GREECE

Number of pages

14

Pages from-to

2909-2922

UT code for WoS article

000377464200035

EID of the result in the Scopus database

2-s2.0-84991737425