Chitosan nanoparticles as delivery system for nasal immunisation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10464869" target="_blank" >RIV/00179906:_____/23:10464869 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/24:00560277 RIV/00216275:25310/23:39918766
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2LC9Z6_IS" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=2LC9Z6_IS</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.31482/mmsl.2022.023" target="_blank" >10.31482/mmsl.2022.023</a>
Alternative languages
Result language
angličtina
Original language name
Chitosan nanoparticles as delivery system for nasal immunisation
Original language description
Nasal immunisation represents an innovative and perspective route of vaccine administration that provides many benefits compared to the more traditional approaches. Since most infections start on mucosal membranes, the mucosal immunisation provides a rational reason for its application. Mucosal delivery for vaccine administration (for example oral or nasal routes) could stimulate both systemic and mucosal immune responses. However, there are still some limitations that should be solved for a broader utilisation of this approach. There is still the necessity to use strongly immunogenic antigens or appropriate adjuvants for the induction of a strong immune response. The use of nanoparticles in the vaccine development could represent a promising approach for the mucosal vaccine research. Nanoparticles could thus serve as delivery vehicles providing to vaccines their unique properties, such as the antigen stabilisation and protection, serve as an adjuvant and elicit an antigen-specific immune response on the target sites.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
<a href="/en/project/LTAUSA19003" target="_blank" >LTAUSA19003: The induction of antiviral immune response after intranasal aplicaton of nanoparticles based vaccine</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Military Medical Science Letters - Vojenské zdravotnické listy
ISSN
0372-7025
e-ISSN
2571-113X
Volume of the periodical
92
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
9
Pages from-to
48-56
UT code for WoS article
—
EID of the result in the Scopus database
2-s2.0-85150370570