Alterations in IFN signaling in cancer and their potential clinical impact

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F03%3A00008023" target="_blank" >RIV/00209805:_____/03:00008023 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/03:00008210

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Alterations in IFN signaling in cancer and their potential clinical impact

Original language description

We here report on the deficient inducibility of STAT1 phosphorylation at Ser-727 and Tyr-701 in response to IFN-?Ń/-gamma in stage II and III melanoma patients. The absence of STAT1 activation at Ser-727 occurred in three quarters of patients. Inductionof STAT1 phosphorylation at Tyr-701 by IFN-alfa was lacking in 63% and by IFN-gamma in 34% of patients.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

<a href="/en/project/GA301%2F03%2F0370" target="_blank" >GA301/03/0370: Analysis of STAT 1 and STAT 3 mediated cytokine signaling in normal and cancer cells</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of molecular medicine

ISSN

1107-3756

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

suppl.1

Country of publishing house

GR - GREECE

Number of pages

1

Pages from-to

"S40"

UT code for WoS article

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EID of the result in the Scopus database

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