Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F03%3A00008027" target="_blank" >RIV/00209805:_____/03:00008027 - isvavai.cz</a>

Alternative codes found

RIV/00209805:_____/03:00008216

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation

Original language description

STAT 1 levels and inducibility of its activated phosphoforms were detected by Western analysis using specific polyclonal and monoclonal antibodies. The study demonstrates STAT 1 functional abnormalities in melanoma cells. On the basis of detail analysesof patient melanoma cells with respect to the inducibility of STAT 1 phosphorylation by IFNs, four categories of patients could be distinguished: a) activation on both S 727 and Y 701, b) not inducible response, c) activation on Y 701 but not on S 727, d) heterogeneous response.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International journal of molecular medicine

ISSN

1107-3756

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

3

Country of publishing house

GR - GREECE

Number of pages

6

Pages from-to

335-340

UT code for WoS article

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EID of the result in the Scopus database

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