A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F13%3A%230000433" target="_blank" >RIV/00209805:_____/13:#0000433 - isvavai.cz</a>
Result on the web
<a href="http://cebp.aacrjournals.org/content/22/9/1620.full.pdf+html" target="_blank" >http://cebp.aacrjournals.org/content/22/9/1620.full.pdf+html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1158/1055-9965.EPI-13-0334" target="_blank" >10.1158/1055-9965.EPI-13-0334</a>

Result language
angličtina
Original language name
A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium
Original language description
Recent findings suggest that alcohol consumption may reduce risk of multiple myeloma. To better understand this relationship, we conducted an analysis of six case-control studies participating in the International Multiple Myeloma Consortium (1,567 cases, 7,296 controls). Summary ORs and 95% confidence intervals (CI) relating different measures of alcohol consumption and multiple myeloma risk were computed by unconditional logistic regression with adjustment for age, race, and study center. Cases were significantly less likely than controls to report ever drinking alcohol (men: OR 1/4 0.72; 95% CI, 0.59-0.89; women: OR 1/4 0.81; 95% CI, 0.68-0.95). The inverse association with multiple myeloma was stronger when comparing current to never drinkers (men:OR 1/4 0.57; 95% CI, 0.45-0.72; women:OR 1/4 0.55; 95% CI, 0.45-0.68), but null among former drinkers. We did not observe an exposure-response relationship with increasing alcohol frequency, duration, or cumulative lifetime consumption. A
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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