A pooled analysis of cigarette smoking and risk of multiple myeloma from the International Multiple Myeloma Consortium

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F15%3A%230000608" target="_blank" >RIV/00209805:_____/15:#0000608 - isvavai.cz</a>
Result on the web
<a href="http://cebp.aacrjournals.org/cgi/pmidlookup?view=long&pmid=25538226" target="_blank" >http://cebp.aacrjournals.org/cgi/pmidlookup?view=long&pmid=25538226</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1158/1055-9965.EPI-14-1145" target="_blank" >10.1158/1055-9965.EPI-14-1145</a>

Result language
angličtina
Original language name
A pooled analysis of cigarette smoking and risk of multiple myeloma from the International Multiple Myeloma Consortium
Original language description
Background: Past investigations of cigarette smoking and multiple myeloma have been underpowered to detect moderate associations, particularly within subgroups. To clarify this association, we conducted a pooled analysis of nine case?control studies in the International Multiple Myeloma Consortium, with individual-level questionnaire data on cigarette smoking history and other covariates. Methods: Using a pooled population of 2,670 cases and 11,913 controls, we computed odds ratios (OR) and 95% confidence intervals (CI) relating smoking to multiple myeloma risk using unconditional logistic regression adjusting for gender, age group, race, education, body mass index, alcohol consumption, and study center. Results: Neither ever smokers (OR, 0.95; 95% CI,0.87?1.05), current smokers (OR, 0.82; 95% CI, 0.73?0.93), nor former smokers (OR, 1.03; 95% CI, 0.92?1.14) had increased risks ofmultiple myeloma compared with never smokers. Analyses of smoking frequency, pack-years, and duration did n
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
<a href="/en/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regional Centre for Applied Molecular Oncology (RECAMO)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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