Long Non-Coding RNAs in Multiple Myeloma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F19%3A00078377" target="_blank" >RIV/00209805:_____/19:00078377 - isvavai.cz</a>
Alternative codes found
RIV/00843989:_____/19:E0107736 RIV/00216224:14110/19:00108519
Result on the web
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468639/pdf/ncrna-05-00013.pdf" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468639/pdf/ncrna-05-00013.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ncrna5010013" target="_blank" >10.3390/ncrna5010013</a>
Alternative languages
Result language
angličtina
Original language name
Long Non-Coding RNAs in Multiple Myeloma
Original language description
Multiple myeloma (MM) is the second most common hematooncological disease of malignant plasma cells in the bone marrow. While new treatment brought unprecedented increase of survival of patients, MM pathogenesis is yet to be clarified. Increasing evidence of expression of long non-coding RNA molecules (lncRNA) linked to development and progression of many tumors suggested their important role in tumorigenesis. To date, over 15,000 lncRNA molecules characterized by diversity of function and specificity of cell distribution were identified in the human genome. Due to their involvement in proliferation, apoptosis, metabolism, and differentiation, they have a key role in the biological processes and pathogenesis of many diseases, including MM. This review summarizes current knowledge of non-coding RNAs (ncRNA), especially lncRNAs, and their role in MM pathogenesis. Undeniable involvement of lncRNAs in MM development suggests their potential as biomarkers.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30204 - Oncology
Result continuities
Project
<a href="/en/project/NV17-29343A" target="_blank" >NV17-29343A: Bone marrow microenvironment analysis in extramedullary relapse of multiple myeloma</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Non-coding RNA
ISSN
2311-553X
e-ISSN
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Volume of the periodical
5
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
15
Pages from-to
"E13"
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85063964711