Elevated prolactin levels in patients with rheumatoid arthritis: association with disease activity and structural damage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A6372" target="_blank" >RIV/00216208:11110/10:6372 - isvavai.cz</a>

Alternative codes found

RIV/00023728:_____/10:#0000064 RIV/00064165:_____/10:6372

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Elevated prolactin levels in patients with rheumatoid arthritis: association with disease activity and structural damage

Original language description

The focus of this study was to evaluate the role of prolactin (PRL) serum and synovial fluid levels in patients suffering from rheumatoid arthritis in the disease activity - clinical, laboratory and X-ray changes. A total of 29 patients with RA and 26 patients with OA were included in the study. The concentration of PRL in the serum and synovial fluid was measured by immunoradiometric assays, and the levels of serum anti-citrullinated protein/peptide autoantibodies (ACPA) and IgM rheumatoid factor (IgM-RF) were analysed by ELISA. Disease activity score (DAS 28) and radiological (Larsen) score were assessed. The levels of PRL in serum (299.55?27.28 vs. 230.59?16.61mIU/l, p=0.041) as well as in synovial fluid (338.85? 33.49 vs. 245.97?21.88mIU/l, p=0.024) were significantly higher in patients with RA than in patients with OA. The findings of increased prolactin levels in patients with RA lead to the assumption that prolactin may play a role in disease severity and the process of joint da

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

<a href="/en/project/NR9292" target="_blank" >NR9292: Prolactin and rheumatoid arthritis</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Clinical and Experimental Rheumatology

ISSN

0392-856X

e-ISSN

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Volume of the periodical

28

Issue of the periodical within the volume

6

Country of publishing house

IT - ITALY

Number of pages

6

Pages from-to

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UT code for WoS article

000286918800008

EID of the result in the Scopus database

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