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Determination of asialotransferrin in the cerebrospinal fluid with the HPLC method

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F10%3A6447" target="_blank" >RIV/00216208:11110/10:6447 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/10:00058961

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Determination of asialotransferrin in the cerebrospinal fluid with the HPLC method

  • Original language description

    Identification of the content of asialotransferrin in the cerebrospinal fluid is a diagnostic method for childhood-onset ataxia and central nervous system hypomyelination (CACH), also known as vanishing white matter disease (VWM), and also for other types of CNS disorders. In our work, we have determined the value of the ratio of the asialo form of transferrin to the total transferrin in the CSF using the commercially used Variant(TM) Bio-Rad system for the determination of carbohydrate-deficient transferrin (CDT) in serum. The peak corresponding to the asialo form of transferrin was identified with electrophoresis with subsequent immunofixation and MALDI-TOF/TOF mass spectrometry.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Scandinavian Journal of Clinical & Laboratory Investigation

  • ISSN

    0036-5513

  • e-ISSN

  • Volume of the periodical

    70

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    NO - NORWAY

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

    000275740900005

  • EID of the result in the Scopus database