HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A8891" target="_blank" >RIV/00216208:11110/11:8891 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/11:8891
Result on the web
<a href="http://dx.doi.org/10.1016/j.jneuroim.2011.04.011" target="_blank" >http://dx.doi.org/10.1016/j.jneuroim.2011.04.011</a>
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event
Original language description
The objectives were to assess the associations between HLA DRB1*1501 status and magnetic resonance imaging (MRI) measures in clinically isolated syndromes (CIS) at the first demyelinating event. Methods: We genotyped 205 CIS patients (age: 29.0 +/- 7.7 years) enrolled in the Observational Study of Early Interferon beta 1-a Treatment in High Risk Subjects after CIS (SET study), a multi-center, clinical study of CIS for rs3135005, a single nucleotide polymorphism associated with HLA DRB1*1501 status. Theinclusion criteria required 2 or more brain MRI lesions and the presence of two or more oligoclonal bands in cerebrospinal fluid.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—

Project
<a href="/en/project/1A8713" target="_blank" >1A8713: Pharmacogenomics - a promising way for reasonable and efficacious multiple sclerosis treatment</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)