Serum S100A12 (EN-RAGE) Levels in Patients with Decreased Renal Function and Subclinical Chronic Inflammatory Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9165" target="_blank" >RIV/00216208:11110/11:9165 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/11:00181727 RIV/00064165:_____/11:9165
Result on the web
<a href="http://dx.doi.org/10.1159/000329291" target="_blank" >http://dx.doi.org/10.1159/000329291</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Serum S100A12 (EN-RAGE) Levels in Patients with Decreased Renal Function and Subclinical Chronic Inflammatory Disease
Original language description
Background: The calcium-binding protein S100A12 (EN-RAGE) causes inflammation through interaction with the multiligand receptor for advanced glycation end products (RAGE). The aim of the study was to determine S100A12 levels and describe their relationship to inflammatory markers in patients with decreased renal function. Methods: The studied group consisted of 46 patients with various degrees of chronic renal insufficiency (CHRI), 31 long-term hemodialysis (HD) patients and 24 healthy controls. S100A12and soluble RAGE were assessed immunochemically (ELISA), and routine biochemical parameters were measured. Results: S100A12 levels were not different in CHRI (166 +/- 140 ng/ml) and HD patients (127 +/- 101 ng/ml) compared to controls (126 +/- 106 ng/ml; p = 0.20, n.s.). In CHRI patients, S100A12 correlated with C-reactive protein (CRP) levels, orosomucoid, and inversely with alpha(2)-macroglobulin. In HD patients, S100A12 correlated with age, CRP, orosomucoid, fibrinogen and leukocyte
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NS10043" target="_blank" >NS10043: Genetic predisposition and new biochemical markers of cardiovascular risk in patients with chronic kidney diseases.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Kidney and Blood Pressure Research
ISSN
1420-4096
e-ISSN
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Volume of the periodical
34
Issue of the periodical within the volume
6
Country of publishing house
CH - SWITZERLAND
Number of pages
8
Pages from-to
457-464
UT code for WoS article
000297128400011
EID of the result in the Scopus database
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