Nicotine influence the motor performance of immature rats in two different sensorimotor tasks

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F11%3A9383" target="_blank" >RIV/00216208:11110/11:9383 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Nicotine influence the motor performance of immature rats in two different sensorimotor tasks

Original language description

The aim of this study was to assess the effect of nicotine on motor performance of immature (12-day-old) rats. We used two sensorimotor tasks (surface righting response and negative geotaxis test) to evaluate the influence of nicotine on animal's motor activity in course of 24 hours. Animals were treated intraperitoneally with two different nicotine doses (0.5 mg/kg and 1.0 mg/kg) and tested in four sessions (1 minute, 10 minutes, 1 hour and 24 hours after the injection). We concluded that nicotine significantly influences the motor behaviour in 12-day-old rats and this effect is dose dependent.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Prague Medical Report

ISSN

1214-6994

e-ISSN

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Volume of the periodical

112

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

177-183

UT code for WoS article

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EID of the result in the Scopus database

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