Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q-syndrome and in Diamond-Blackfan anemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A00013501" target="_blank" >RIV/00216208:11110/13:00013501 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/13:#0000605 RIV/00023736:_____/13:00010001 RIV/00064165:_____/13:00013501
Result on the web
<a href="http://dx.doi.org/10.1007/s00277-012-1568-1" target="_blank" >http://dx.doi.org/10.1007/s00277-012-1568-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00277-012-1568-1" target="_blank" >10.1007/s00277-012-1568-1</a>
Alternative languages
Result language
angličtina
Original language name
Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q-syndrome and in Diamond-Blackfan anemia
Original language description
Friend leukemia virus integration 1 (Fli1) and erythroid Krüppel-like factor (EKLF) participate under experimental conditions in the differentiation of megakaryocytic and erythroid progenitor in cooperation with other transcription factors, cytokines, cytokine receptors, and microRNAs. Defective erythropoiesis with refractory anemia and effective megakaryopoiesis with normal or increased platelet count is typical for 5q- syndrome. We decided to evaluate the roles of EKLF and Fli1 in the pathogenesis ofthis syndrome and of another ribosomopathy, Diamond-Blackfan anemia (DBA).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13836" target="_blank" >NT13836: The study of the myelodysplastic syndrome pathogenesis in patients with isolated del(5q) abnormality and the analysis of the effect of lenalidomide</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Annals of Hematology
ISSN
0939-5555
e-ISSN
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Volume of the periodical
92
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
11-18
UT code for WoS article
000313068700002
EID of the result in the Scopus database
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