Cerebellar rTMS stimulation may induce prolonged clinical benefits in essential tremor, and subjacent changes in functional connectivity: An open label trial
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189414" target="_blank" >RIV/00216208:11110/13:10189414 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.brs.2012.04.009" target="_blank" >http://dx.doi.org/10.1016/j.brs.2012.04.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.brs.2012.04.009" target="_blank" >10.1016/j.brs.2012.04.009</a>
Alternative languages
Result language
angličtina
Original language name
Cerebellar rTMS stimulation may induce prolonged clinical benefits in essential tremor, and subjacent changes in functional connectivity: An open label trial
Original language description
Background: Cerebello-thalamo-cortical (CTC) pathways dysfunction is involved in pathological oscillations causing tremor in essential tremor (ET). Low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) of the cerebellum can effectivelymodulate the cerebellar output. Objective: As one session of rTMS can induce a brief improvement, we hypothesized that repeated sessions might have a cumulative and potentially long-term therapeutic effect on ET. We assessed, in an open label trial, theefficacy of one-week rTMS treatment on tremor and on the motor-CTC dysfunction in ET patients. Methods: Resting-state fMRI functional connectivity was used as an indicator of CTC network integrity in 11 ET patients and 11 healthy subjects. Resting-statefMRI connectivity was quantified at baseline in patients and control subjects between the cerebellum and the motor network, and between the cerebellum and the default brain network (DBN) taken as control. The fMRI study was repeated in p
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Brain Stimulation
ISSN
1935-861X
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
175-179
UT code for WoS article
000316840000012
EID of the result in the Scopus database
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