Soluble receptor for advanced glycation end products predicts 28-day mortality in critically ill patients with sepsis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189582" target="_blank" >RIV/00216208:11110/13:10189582 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/13:10189582
Result on the web
<a href="http://dx.doi.org/10.3109/00365513.2013.849357" target="_blank" >http://dx.doi.org/10.3109/00365513.2013.849357</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/00365513.2013.849357" target="_blank" >10.3109/00365513.2013.849357</a>
Alternative languages
Result language
angličtina
Original language name
Soluble receptor for advanced glycation end products predicts 28-day mortality in critically ill patients with sepsis
Original language description
Objective. Multiple biomarkers are used to assess sepsis severity and prognosis. Increased levels of the soluble receptor for advanced glycation end products (sRAGE) were previously observed in sepsis but also in end-organ injury without sepsis. We evaluated associations between sRAGE and (i) 28-day mortality, (ii) sepsis severity, and (iii) individual organ failure. Traditional biomarkers procalcitonin (PCT), C-reactive protein (CRP) and lactate served as controls. Methods. sRAGE, PCT, CRP, and lactatelevels were observed on days 1 (D1) and 3 (D3) in 54 septic patients. We also assessed the correlation between the biomarkers and acute respiratory distress syndrome (ARDS), acute kidney injury (AKI) and acute heart failure. Results. There were 38 survivors and 16 non-survivors. On D1, non-survivors had higher sRAGE levels than survivors (p = 0.027). On D3, sRAGE further increased only in non-survivors (p < 0.0001) but remained unchanged in survivors. Unadjusted odds ratio (OR) for 28-d
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scandinavian Journal of Clinical and Laboratory Investigation
ISSN
0036-5513
e-ISSN
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Volume of the periodical
73
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
650-660
UT code for WoS article
000326977500008
EID of the result in the Scopus database
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