Mitochondrial respiration in blood platelets of depressive patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10190649" target="_blank" >RIV/00216208:11110/13:10190649 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/13:10190649
Result on the web
<a href="http://dx.doi.org/10.1016/j.mito.2013.05.005" target="_blank" >http://dx.doi.org/10.1016/j.mito.2013.05.005</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mito.2013.05.005" target="_blank" >10.1016/j.mito.2013.05.005</a>
Alternative languages
Result language
angličtina
Original language name
Mitochondrial respiration in blood platelets of depressive patients
Original language description
Recent evidences include mitochondrial dysfunctions in pathophysiology of mood disorders. We examined association between depressive disorders and mitochondrial respiration using both intact and permeabilized blood platelets. In intact platelets, physiological respiration, maximal capacity of electron transport system and respiratory rate after complex I inhibition were decreased in depressive patients, who reached partial remission, compared to healthy controls. Respiratory rates were unchanged in several respiratory states in permeabilized platelets. Results indicate that changes in respiratory rate in intact platelets can be used as biological marker of depressive disorder. The hypothesis that decreased mitochondrial respiratory rate participate inpathophysiology of depression was supported.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mitochondrion
ISSN
1567-7249
e-ISSN
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Volume of the periodical
13
Issue of the periodical within the volume
6
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
6
Pages from-to
795-800
UT code for WoS article
000327280500029
EID of the result in the Scopus database
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