Evaluation of speech impairment in early stages of Parkinson's disease: a prospective study with the role of pharmacotherapy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10190954" target="_blank" >RIV/00216208:11110/13:10190954 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/13:00202267 RIV/00064165:_____/13:10190954
Result on the web
<a href="http://dx.doi.org/10.1007/s00702-012-0853-4" target="_blank" >http://dx.doi.org/10.1007/s00702-012-0853-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00702-012-0853-4" target="_blank" >10.1007/s00702-012-0853-4</a>

Result language
angličtina
Original language name
Evaluation of speech impairment in early stages of Parkinson's disease: a prospective study with the role of pharmacotherapy
Original language description
Despite the initial reports showing beneficial effects of dopaminergic treatment on speech in Parkinson's disease (PD), more recent studies based upon valid measurements have not approved any improvement of speech performance under pharmacotherapy. The aim of this study was to analyze the effect of treatment initiation on the progression of speech impairment in PD, using novel evaluation criteria. Nineteen de novo patients with PD were tested and retested within 2 years after the introduction of antiparkinsonian therapy. As controls, 19 age-matched individuals were recorded. Speech examination included sustained phonation, fast syllable repetition, reading text, and monolog. Quantitative acoustic analyses of the key aspects of speech based on Gaussiankernel distribution, statistical decision-making theory, and healthy speech observation were used to assess the improvement or deterioration of speech. A trend for speech performances to improve was demonstrated after treatment mainly in
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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