Toxic Shock Syndrome and Persistent Immune Activation in an HIV-Positive Patient

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10191056" target="_blank" >RIV/00216208:11110/13:10191056 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/13:#0000225
Result on the web
<a href="http://dx.doi.org/10.2174/1570162X113119990045" target="_blank" >http://dx.doi.org/10.2174/1570162X113119990045</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2174/1570162X113119990045" target="_blank" >10.2174/1570162X113119990045</a>

Result language
angličtina
Original language name
Toxic Shock Syndrome and Persistent Immune Activation in an HIV-Positive Patient
Original language description
The case of an HIV-positive treatment-naive male with toxic shock syndrome (TSS) is presented herein. The course of TSS was favorable; however, the patient had extremely high plasma levels of MCP-1 and CD38 and HLA-DR expression on CD8+ T cells during the acute illness. Furthermore, the numbers of CD8+ T cells were reduced and CD4+ T cells remained stable during acute illness in comparison to baseline values. MCP-1 and HLA-DR gradually decreased, but they were still elevated after a month, whereas the number of circulating CD8+ T cells increased more than fivefold. CD38 expression remained stable during this period. A further decrease in CD38, HLA-DR and MCP-1 was noted five months after the initiation of antiretroviral therapy.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FN - Epidemiology, infection diseases and clinical immunology
OECD FORD branch
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Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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