Cytokines and Chemokines as Biomarkers of Community-Acquired Bacterial Infection

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10191060" target="_blank" >RIV/00216208:11110/13:10191060 - isvavai.cz</a>

Alternative codes found

RIV/00064211:_____/13:#0000223

Result on the web

<a href="http://dx.doi.org/10.1155/2013/190145" target="_blank" >http://dx.doi.org/10.1155/2013/190145</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2013/190145" target="_blank" >10.1155/2013/190145</a>

Result language

angličtina

Original language name

Cytokines and Chemokines as Biomarkers of Community-Acquired Bacterial Infection

Original language description

Routinely used biomarkers of bacterial etiology of infection, such as C-reactive protein and procalcitonin, have limited usefulness for evaluation of infections since their expression is enhanced by a number of different conditions. Therefore, several inflammatory cytokines and chemokines were analyzed with sera from patients hospitalized for moderate bacterial and viral infectious diseases. In total, 57 subjects were enrolled: 21 patients with community-acquired bacterial infections, 26 patients with viral infections, and 10 healthy subjects (control cohorts). The laboratory analyses were performed using Luminex technology, and the following molecules were examined: IL-1Ra, IL-2, IL-4, IL-6, IL-8, TNF-alpha, INF-gamma, MIP-1 beta, and MCP-1. Bacterialetiology of infection was associated with significantly (P < 0.001) elevated serum concentrations of IL-1Ra, IL-2, IL-6, and TNF-alpha in comparison to levels observed in the sera of patients with viral infections. In the patients with b

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FN - Epidemiology, infection diseases and clinical immunology

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mediators of Inflammation

ISSN

0962-9351

e-ISSN

—

Volume of the periodical

Neuveden.

Issue of the periodical within the volume

Aut

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

—

UT code for WoS article

000318080600001

EID of the result in the Scopus database

—