Microscopic notes on the perinucleolar chromatin region in immature and mature human B-leukemia lymphocytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10195042" target="_blank" >RIV/00216208:11110/13:10195042 - isvavai.cz</a>

Alternative codes found

RIV/00023736:_____/13:00010685

Result on the web

<a href="http://dx.doi.org/10.4149/neo_2013_037" target="_blank" >http://dx.doi.org/10.4149/neo_2013_037</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/neo_2013_037" target="_blank" >10.4149/neo_2013_037</a>

Result language

angličtina

Original language name

Microscopic notes on the perinucleolar chromatin region in immature and mature human B-leukemia lymphocytes

Original language description

Perinucleolar region was studied in lymphocytes of patients suffering from chronic B lymphocytic leukemia to provide more information on the perinucleolar-condensed chromatin - heterochromatin - during the maturation of these cells. The perinucleolar heterochromatin of lymphocytes in smear preparations was visualized using a simple, but sensitive cytochemical method for the demonstration of DNA. The perinucleolar heterochromatin was also easily visible as unstained perinucleolar regions in specimens stained for RNA. In addition, the perinucleolar heterochromatin of lymphocytes was distinct and apparent in the transmission electron microscope using conventional as well as cytochemical methods for visualization of chromatin structures. Despite the greatvariability, the maturation of leukemic lymphocytes was accompanied by an increased width of the perinucleolar heterochromatin shell. It seems to be also interesting that the perinucleolar region of both immature as well as mature leukemi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neoplasma

ISSN

0028-2685

e-ISSN

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Volume of the periodical

60

Issue of the periodical within the volume

3

Country of publishing house

SK - SLOVAKIA

Number of pages

6

Pages from-to

284-289

UT code for WoS article

000323235300007

EID of the result in the Scopus database

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