Strategies to manage hepatitis C virus (HCV) disease burden

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10283782" target="_blank" >RIV/00216208:11110/14:10283782 - isvavai.cz</a>

Alternative codes found

RIV/61383082:_____/14:#0000269 RIV/00216224:14110/14:00075456 RIV/65269705:_____/14:00062683 RIV/00023001:_____/14:00058938 RIV/75010330:_____/14:00010740

Result on the web

<a href="http://dx.doi.org/10.1111/jvh.12249" target="_blank" >http://dx.doi.org/10.1111/jvh.12249</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jvh.12249" target="_blank" >10.1111/jvh.12249</a>

Result language

angličtina

Original language name

Strategies to manage hepatitis C virus (HCV) disease burden

Original language description

The number of hepatitis C virus (HCV) infections is projected to decline while those with advanced liver disease will increase. A modeling approach was used to forecast two treatment scenarios: (i) the impact of increased treatment efficacy while keepingthe number of treated patients constant and (ii) increasing efficacy and treatment rate. This analysis suggests that successful diagnosis and treatment of a small proportion of patients can contribute significantly to the reduction of disease burden inthe countries studied. The largest reduction in HCV-related morbidity and mortality occurs when increased treatment is combined with higher efficacy therapies, generally in combination with increased diagnosis. With a treatment rate of approximately 10%,this analysis suggests it is possible to achieve elimination of HCV (defined as a >90% decline in total infections by 2030). However, for most countries presented, this will require a 3-5 fold increase in diagnosis and/or treatment. Thus

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Viral Hepatitis

ISSN

1352-0504

e-ISSN

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Volume of the periodical

21

Issue of the periodical within the volume

Supplement 1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

30

Pages from-to

60-89

UT code for WoS article

000333893200004

EID of the result in the Scopus database

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