The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284342" target="_blank" >RIV/00216208:11110/14:10284342 - isvavai.cz</a>

Alternative codes found

RIV/61383082:_____/14:#0000272 RIV/00216224:14110/14:00075468 RIV/65269705:_____/14:00062681 RIV/00023001:_____/14:00059022 RIV/75010330:_____/14:00010739

Result on the web

<a href="http://dx.doi.org/10.1111/jvh.12248" target="_blank" >http://dx.doi.org/10.1111/jvh.12248</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jvh.12248" target="_blank" >10.1111/jvh.12248</a>

Result language

angličtina

Original language name

The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

Original language description

The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the modelwas used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013-2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm,the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late-stage liver disease is projected to increase. This study concluded that the currenttreatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver-related deaths from increasing.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

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Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Viral Hepatitis

ISSN

1352-0504

e-ISSN

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Volume of the periodical

21

Issue of the periodical within the volume

Supp. 1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

26

Pages from-to

34-59

UT code for WoS article

000333893200003

EID of the result in the Scopus database

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