Podoplanin (D2-40) is a Reliable Marker of Urinary Bladder Myofibroblasts (Telocytes)

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10285326" target="_blank" >RIV/00216208:11110/14:10285326 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/14:10285326
Result on the web
<a href="http://fb.cuni.cz/file/5764/fb2014a0051.pdf" target="_blank" >http://fb.cuni.cz/file/5764/fb2014a0051.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Podoplanin (D2-40) is a Reliable Marker of Urinary Bladder Myofibroblasts (Telocytes)
Original language description
We evaluated the expression of podoplanin in ?-smooth muscle actin positive myofibroblasts producing the suburothelial layer in tunica propria of the urinary bladder that have some similar features with telocytes. We observed positive reaction not only in bioptic specimens from women with interstitial cystitis, but also in a control group of women and men treated for pathological bladder lesion different from intersititial cystitis. Our findings suggest that D2-40 can be used as a complementary immunostainer to ?-smooth muscle actin on urinary bladder biopsies from patients with interstitial cystitis.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Project
<a href="/en/project/NT12137" target="_blank" >NT12137: Correlation between pelvic pain syndrome in interstitial cystitis and histopathology findings, urinary bladder wall visceral nerve axonopathy, beta-HCG expression in urothelium, and microbial findings in biopsy sample</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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