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Intracranial Pressure Declines During Cardiopulmonary Resuscitation in Animal Model

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10287685" target="_blank" >RIV/00216208:11110/14:10287685 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11510/14:10287685

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Intracranial Pressure Declines During Cardiopulmonary Resuscitation in Animal Model

  • Original language description

    Intracranial hypertension represents a significant risk factor of poor neurological outcome in critically ill, specifically those with craniotrauma. Methods: In a porcine model of cardiac arrest (CA) the dynamics of intracranial pressure (ICP) was studied. Threeminutes of untreated CA were followed by 5-minutes of cardiopulmonary resuscitation (CPR) with chest compressions and mechanical ventilation. No other interventions were allowed since out-of-hospital resuscitation was simulated. Throughout the protocol the ICP, arterial and venous pressures and carotid blood flow were continuously recorded. Results: During cardiac arrest ICP increased to 27 +/- 4.8 mmHg, i.e. hypertensive values. Mechanical chest compressions resulted in a transient ICP increasefollowed by a steady decline at approximately 2.25 mmHg/min. By five minutes of CPR intracranial pressure reached prearrest values despite significant elevation of central venous pressure (39 mmHg) and gradual decrease of arterial pressu

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP407%2F10%2F1624" target="_blank" >GAP407/10/1624: Identification of limit effects of hypokinetic enviromental stress on human sensomotoric reactions reliability</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedizinische Technik. Biomedical engineering

  • ISSN

    0013-5585

  • e-ISSN

  • Volume of the periodical

    59

  • Issue of the periodical within the volume

    S1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    3

  • Pages from-to

    "S1001"-"S1003"

  • UT code for WoS article

    000350405700430

  • EID of the result in the Scopus database