Intracranial Pressure Declines During Cardiopulmonary Resuscitation in Animal Model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11510%2F14%3A10288870" target="_blank" >RIV/00216208:11510/14:10288870 - isvavai.cz</a>
Result on the web
<a href="http://conference.vde.com/bmt-2014/documents/bmt%202014%20dokumente/bmt_2014_program.pdf" target="_blank" >http://conference.vde.com/bmt-2014/documents/bmt%202014%20dokumente/bmt_2014_program.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Intracranial Pressure Declines During Cardiopulmonary Resuscitation in Animal Model
Original language description
Intracranial hypertension represents a significant risk factor of poor neurological outcome in critically ill, specifically those with craniotrauma. Methods: In a porcine model of cardiac arrest (CA) the dynamics of intracranial pressure (ICP) was studied. Threeminutes of untreated CA were followed by 5-minutes of cardiopulmonary resuscitation (CPR) with chest compressions and mechanical ventilation. No other interventions were allowed since out-of-hospital resuscitation was simulated. Throughout the protocol the ICP, arterial and venous pressures and carotid blood flow were continuously recorded. Results: During cardiac arrest ICP increased to 27 +/- 4.8 mmHg, i.e. hypertensive values. Mechanical chest compressions resulted in a transient ICP increasefollowed by a steady decline at approximately 2.25 mmHg/min. By five minutes of CPR intracranial pressure reached prearrest values despite significant elevation of central venous pressure (39 mmHg) and gradual decrease of arterial pressu
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP407%2F10%2F1624" target="_blank" >GAP407/10/1624: Identification of limit effects of hypokinetic enviromental stress on human sensomotoric reactions reliability</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů