Altered Immunity in Endometriosis: What Came First?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10378713" target="_blank" >RIV/00216208:11110/18:10378713 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/18:10378713 RIV/00669806:_____/18:10378713
Result on the web
<a href="https://doi.org/10.1080/08820139.2018.1467926" target="_blank" >https://doi.org/10.1080/08820139.2018.1467926</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/08820139.2018.1467926" target="_blank" >10.1080/08820139.2018.1467926</a>
Alternative languages
Result language
angličtina
Original language name
Altered Immunity in Endometriosis: What Came First?
Original language description
Background: This study was conducted to summarize current knowledge of the changes within the immune system, from action of macrophages, lymphocytes and NK cells to biological effects of their products. Endometriosis is a complex gynecological disorder defined as a presence of endometrial tissue outside the uterus affecting over 5 million reproductive-aged women in the U.S. alone.Result: In recent years, the potential role of the immune system in the development of endometriosis has increasingly gained attention. Data summarized in our study showed that the most relevant immunocytes are macrophages residing inside the peritoneal cavity and the ratios of Th1 to Th2 cells. Another crucial immunological parameter is the balance in production of cytokines and chemoatractants.Conclusions: This review confirms that despite decades of intensive research, the involvement of the immune system remains elusive, as we can recognize the changes, but still do not understand if these changes represent the results of endometriosis or if they are contributing factors. Based on these findings, we also discuss new treatment possibilities.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30102 - Immunology
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Immunological Investigations
ISSN
0882-0139
e-ISSN
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Volume of the periodical
47
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
14
Pages from-to
569-582
UT code for WoS article
000438120000004
EID of the result in the Scopus database
2-s2.0-85049674238