Decrease of muscle strength in vascular access hand due to silent ischaemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10383510" target="_blank" >RIV/00216208:11110/18:10383510 - isvavai.cz</a>
Alternative codes found
RIV/00064165:_____/18:10383510
Result on the web
<a href="https://doi.org/10.1177/1129729818763287" target="_blank" >https://doi.org/10.1177/1129729818763287</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1177/1129729818763287" target="_blank" >10.1177/1129729818763287</a>
Alternative languages
Result language
angličtina
Original language name
Decrease of muscle strength in vascular access hand due to silent ischaemia
Original language description
Background: Creation of vascular access leads to considerable local haemodynamic changes with decreased hand perfusion. Distal limb tissues then represent a model of hand ischaemia effect on muscles. The aim of our study was to investigate how the presence of vascular access influences the hand muscle strength in end-stage renal disease patients. Methods: We included 52 chronically haemodialysed patients with upper limb access without clinical signs of hand ischaemia. Muscle strength was evaluated by dynamometry. Finger pressure was measured on the second and fourth fingers and averaged for further analysis. Thenar tissue oxygenation (rSO(2)) was analysed using near-infrared spectroscopy. All examinations were performed in both the hands. Basic laboratory analysis was added. Data were processed with unpaired t-test and correlation analysis. Results: Hands with dialysis access had lower values of handgrip strength (54.2 +/- 29.1 lbs vs 48.6 +/- 23.4 lbs, p = 0.0006), systolic finger pressure (127.1 +/- 32.0 mmHg vs 101.4 +/- 31.6 mmHg, p < 10(-8)) and of thenar rSO(2) (45.8% +/- 12.9% vs 42.5% +/- 13.3%, p = 0.002). Muscle strength (handgrip) was directly related to the thenar oxygenation (r = 0.36; p = 0.014) and to the finger systolic pressure (r = 0.38; p = 0.007) on the access extremity. On the extremity without dialysis access, handgrip strength was inversely related to patient's age (r = -0.41, p = 0.003), dialysis vintage (r = -0.32, p = 0.02) and red cell distribution width (r = -0.37, p = 0.01). Conclusion: The presence of dialysis access leads to the decrease of finger pressure, oxygenation, and also muscle strength even in the absence of clinically overt hand ischaemia. All these parameters are interrelated. This study underlines the consequences of inadequate muscle perfusion.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30201 - Cardiac and Cardiovascular systems
Result continuities
Project
<a href="/en/project/NV17-31796A" target="_blank" >NV17-31796A: Tissue hypoxia in patients with chronic kidney disease – metabolic and hemodynamic associations</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
The Journal of Vascular Access
ISSN
1129-7298
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
6
Country of publishing house
IT - ITALY
Number of pages
5
Pages from-to
573-577
UT code for WoS article
000450363300010
EID of the result in the Scopus database
2-s2.0-85052607297