Tissue ischemia worsens during hemodialysis in end-stage renal disease patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F17%3A10361956" target="_blank" >RIV/00216208:11110/17:10361956 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/17:10361956

Result on the web

<a href="http://dx.doi.org/10.5301/jva.5000630" target="_blank" >http://dx.doi.org/10.5301/jva.5000630</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5301/jva.5000630" target="_blank" >10.5301/jva.5000630</a>

Result language

angličtina

Original language name

Tissue ischemia worsens during hemodialysis in end-stage renal disease patients

Original language description

Background: Cognitive deficit is a common problem in end-stage renal disease (ESRD) patients. Ultrafiltration and hemodialysis lead to profound hemodynamic changes. The aim of this pilot study was to describe brain and hand oxygenation values in ESRD patients and their changes during hemodialysis. Methods: Twenty-seven patients treated by chronic hemodialysis and 17 controls patients of the same age were included in the study. Regional saturation of oxygen (SrO2) was measured at the brain frontal lobe and at the hand with dialysis access using the INVOS 5100C. In 17 of ESRD patients, SrO2 was also monitored throughout hemodialysis. Finger systolic blood pressure and basic hemodialysis and laboratory data were collected. Results: Dialysis patients had lower brain and also hand SrO2 values at rest (51.5 +/- 10.9 vs. 68 +/- 7%, p&lt; 0.0001 and 55 +/- 16 vs. 66 +/- 8%, p = 0.03, respectively). Both values further decreased during the first 35 minutes of hemodialysis (brain SrO2 to 47 +/- 8%, p&lt; 0.0001 and hand to 45 +/- 14%, p&lt; 0.0001, respectively). The brain SrO2 decrease was related to the ultrafiltration rate, the hand SrO2 decrease to the finger pressure and to blood hemoglobin. Conclusions: Chronic dialysis patients suffer from tissue ischemia and that even worsens after the beginning of hemodialysis. This observation may contribute to the understanding of cognitive deficit etiology.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Journal of Vascular Access

ISSN

1129-7298

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

1

Country of publishing house

IT - ITALY

Number of pages

5

Pages from-to

47-51

UT code for WoS article

000395837400015

EID of the result in the Scopus database

2-s2.0-85010332836