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DNA adducts, strand breaks and micronuclei in mice exposed to styrene by inhalation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F01%3A00110189" target="_blank" >RIV/00216208:11120/01:00110189 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/01:19010044 RIV/60162694:G16__/01:00000575 RIV/00023795:_____/01:00004788 RIV/60162694:G38__/01:00000575

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA adducts, strand breaks and micronuclei in mice exposed to styrene by inhalation

  • Original language description

    Genotoxic and clastogenic effects of styrene were studied in mice. Male NMRI mice were exposed by inhalation to styrene for 21, 7, 3 and 1 days. Followed parameters included styrene in blood, specific styrene oxide, induced DNA adducts, strand breaks andmicronuclei. Induced DNA adducts correlated with styrene concentration in blood. An interesting link has been found between single strand breaks in bone marrow and frequencies of micronuclei.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    DN - Environmental impact on health

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA313%2F99%2F1460" target="_blank" >GA313/99/1460: Mechanisms of genotoxic effects and prospects to the evaluation of individual susceptibility to styrene exposure</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemico-Biological Interactions

  • ISSN

    0009-2797

  • e-ISSN

  • Volume of the periodical

    137

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    25

  • Pages from-to

    213-237

  • UT code for WoS article

  • EID of the result in the Scopus database