Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F04%3A00001146" target="_blank" >RIV/00216208:11120/04:00001146 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Morphological evidence of collateral sprouting of intact afferent and motor axons of the rat ulnar nerve demonstrated by one type of tracer molecule

Original language description

In our experimental paradigm we sutured the distal stump of a transected musculocutaneous nerve to an intact ulnar nerve of the rat in an end-to-side fashion. We demonstrated the formation of collateral sprouts from intact afferent and motor axons by application of one type of molecule conjugated by two different fluorophores (Fluoro-Ruby and Fluoro-Emerald). Fluoro-Ruby and Fluoro-Emerald were applied distal to end-to-side suture into fresh cut ends of the ulnar and musculocutaneous nerves, respectively. Formation of collateral sprouts was evidenced by findings of mixed (a yellow to orange color) fluorescence labeling of spinal motoneurons and dorsal root ganglia neurons. Colocalization of two different tracers retrogradely transported to the neuronswas verified by the individual green and red fluorescence profiles analyzed by means of the computer-assisted image-analyzing system.

Czech name

Morfologický průkaz kolaterálního růstu intaktních aferentních a motorických axonů krysího ulnárního nervu demonstrovaný jedním typem molekuly izotopového indikátoru

Czech description

Práce popisuje morfologický průkaz kolaterálního růstu intaktních aferentních a motorických axonů krysího ulnárního nervu demonstrovaný jedním typem molekuly izotopového indikátoru

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/NF6658" target="_blank" >NF6658: Alternative approaches in brachial plexus reconstruction and experimental evaluation of various neurotrophic factors action on direct and collateral reinnervation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2004

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Anatomy

ISSN

0940-9602

e-ISSN

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Volume of the periodical

186

Issue of the periodical within the volume

3

Country of publishing house

DE - GERMANY

Number of pages

4

Pages from-to

231-234

UT code for WoS article

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EID of the result in the Scopus database

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