Ciliary neurotrophic factor promotes motor reinnervation of the musculocutaneous nerve in an experimental model of end-to-side neurorrhaphy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003179" target="_blank" >RIV/00216208:11120/11:00003179 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/11:00053056 RIV/00064173:_____/11:#0000275
Result on the web
<a href="http://dx.doi.org/10.1186/1471-2202-12-58" target="_blank" >http://dx.doi.org/10.1186/1471-2202-12-58</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/1471-2202-12-58" target="_blank" >10.1186/1471-2202-12-58</a>
Alternative languages
Result language
angličtina
Original language name
Ciliary neurotrophic factor promotes motor reinnervation of the musculocutaneous nerve in an experimental model of end-to-side neurorrhaphy
Original language description
The distal stump of rat transected musculocutaneous nerve (MCN) was attached in an end-to-side fashion with ulnar nerve. CNTF, Cerebrolysin and vehiculum were administered intrathecally for 2 weeks, and all animals were allowed to survive for 2 months from operation. Numbers of spinal motor and dorsal root ganglia neurons were estimated following their retrograde labeling by Fluoro-Ruby and Fluoro-Emerald applied to ulnar and musculocutaneous nerve, respectively. Reinnervation of biceps brachii muscleswas assessed by electromyography, behavioral test, and diameter and myelin sheath thickness of regenerated axons. Vehiculum or Cerebrolysin administration resulted in significantly higher numbers of myelinated axons regenerated into the MCN stumps compared with CNTF treatment. By contrast, the mean diameter of the myelinated axons and their myelin sheath thickness in the cases of Cerebrolysin-or CNTF-treated animals were larger than were those for rats treated with vehiculum. CNTF treatm
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Neuroscience
ISSN
1471-2202
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
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Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
1-12
UT code for WoS article
000293476600001
EID of the result in the Scopus database
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