Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907967" target="_blank" >RIV/00216208:11120/13:43907967 - isvavai.cz</a>

Alternative codes found

RIV/00023752:_____/13:43914514

Result on the web

<a href="http://dx.doi.org/10.1177/1352458513488232" target="_blank" >http://dx.doi.org/10.1177/1352458513488232</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1177/1352458513488232" target="_blank" >10.1177/1352458513488232</a>

Result language

angličtina

Original language name

Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis

Original language description

The choice of appropriate control group(s) is critical in cerebrospinal fluid (CSF) biomarker research in multiple sclerosis (MS). There is a lack of definitions and nomenclature of different control groups and a rationalized application of different control groups. We here propose consensus definitions and nomenclature for the following groups: healthy controls (HCs), spinal anesthesia subjects (SASs), inflammatory neurological disease controls (INDCs), peripheral inflammatory neurological disease controls (PINDCs), non-inflammatory neurological controls (NINDCs), symptomatic controls (SCs). Furthermore, we discuss the application of these control groups in specific study designs, such as for diagnostic biomarker studies, prognostic biomarker studiesand therapeutic response studies. Application of these uniform definitions will lead to better comparability of biomarker studies and optimal use of available resources. This will lead to improved quality of CSF biomarker research in MS a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/NT13183" target="_blank" >NT13183: Brief psychometric instruments for early diagnosis of Alzheimer's disease in senior population</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Multiple Sclerosis Journal

ISSN

1352-4585

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

13

Country of publishing house

GB - UNITED KINGDOM

Number of pages

8

Pages from-to

1802-1809

UT code for WoS article

000326893900021

EID of the result in the Scopus database

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