Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33155746" target="_blank" >RIV/61989592:15110/15:33155746 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/15:#0000950

Result on the web

<a href="http://dx.doi.org/10.1007/s00702-014-1244-9" target="_blank" >http://dx.doi.org/10.1007/s00702-014-1244-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-014-1244-9" target="_blank" >10.1007/s00702-014-1244-9</a>

Result language

angličtina

Original language name

Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study.

Original language description

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Autoimmune inflammation is common in the early stages of MS. This stage is followed by the neurodegenerative process. The result of these changes is axon andmyelin breakdown. Although MS is according to McDonald's revised diagnostic criteria primarily a clinical diagnosis, paraclinical investigation methods are an important part in the diagnosis of MS. In common practice, magnetic resonance imaging of the brain and spinal cord, examination of cerebrospinal fluid (CSF) and examination of visual evoked potentials are used. There are an increasing number of studies dealing with biomarkers in CSF and their role in the diagnosis and treatment of MS. We hypothesized that the levels of some markers could be changed in MS in comparison with controls. We studied five inflammatory markers [interleukin-6 (IL-6), interleukin-8, interleukin-10 (IL-10), beta-2-microglobulin, orosomucoid]. CSF and serum l

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Volume of the periodical

2015

Issue of the periodical within the volume

122

Country of publishing house

AT - AUSTRIA

Number of pages

5

Pages from-to

273-277

UT code for WoS article

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EID of the result in the Scopus database

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