Effects of Ferrofluid and Phytoalexin Spirobrassinin on Thioflavin-T-Based Fluorescence in Cerebrospinal Fluid of the Elderly and Multiple Sclerosis Patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908864" target="_blank" >RIV/00216208:11120/14:43908864 - isvavai.cz</a>
Alternative codes found
RIV/00023752:_____/14:43914592
Result on the web
<a href="http://dx.doi.org/10.1007/s11064-014-1340-0" target="_blank" >http://dx.doi.org/10.1007/s11064-014-1340-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11064-014-1340-0" target="_blank" >10.1007/s11064-014-1340-0</a>
Alternative languages
Result language
angličtina
Original language name
Effects of Ferrofluid and Phytoalexin Spirobrassinin on Thioflavin-T-Based Fluorescence in Cerebrospinal Fluid of the Elderly and Multiple Sclerosis Patients
Original language description
It is well known that misfolded peptides/proteins can play a role in processes of normal ageing and in the pathogenesis of many diseases including Alzheimer's disease. Previously, we evaluated samples of cerebrospinal fluid from patients with Alzheimer'sdisease and multiple sclerosis by means of thioflavin-T-based fluorescence. We observed attenuated effects of magnetite nanoparticles operated via anti-aggregation actions on peptides/proteins from patients with Alzheimer's disease but not from those with multiple sclerosis when compared to age-related controls. In this study, we have evaluated the in vitro effects of anti-aggregation operating ferrofluid and phytoalexin spirobrassinin in the cerebrospinal fluid of patients with multiple sclerosis andAlzheimer's disease. We have found significant differences in native fluorescence (lambda excitation = 440 nm, lambda emission = 485 nm) of samples among particular groups (young controls < multiple sclerosis, Alzheimer's disease < old co
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neurochemical Research
ISSN
0364-3190
e-ISSN
—
Volume of the periodical
39
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
1502-1510
UT code for WoS article
000340401200013
EID of the result in the Scopus database
—