Human papillomavirus DNA prevalence and type distribution in anal carcinomas worldwide
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909122" target="_blank" >RIV/00216208:11120/15:43909122 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/15:10295961 RIV/00179906:_____/15:10295961
Result on the web
<a href="http://dx.doi.org/10.1002/ijc.28963" target="_blank" >http://dx.doi.org/10.1002/ijc.28963</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/ijc.28963" target="_blank" >10.1002/ijc.28963</a>
Alternative languages
Result language
angličtina
Original language name
Human papillomavirus DNA prevalence and type distribution in anal carcinomas worldwide
Original language description
Knowledge about human papillomaviruses (HPV) types involved in anal cancers in some world regions is scanty. Here, we describe the HPV DNA prevalence and type distribution in a series of invasive anal cancers and anal intraepithelial neoplasias (AIN) grades 2/3 from 24 countries. We analyzed 43 AIN 2/3 cases and 496 anal cancers diagnosed from 1986 to 2011. After histopathological evaluation of formalin-fixed paraffin-embedded samples, HPV DNA detection and genotyping was performed using SPF-10/DEIA/LiPA(25) system (version 1). A subset of 116 cancers was further tested for p16(INK4a) expression, a cellular surrogate marker for HPV-associated transformation. Prevalence ratios were estimated using multivariate Poisson regression with robust variance inthe anal cancer data set. HPV DNA was detected in 88.3% of anal cancers (95% confidence interval [CI]: 85.1-91.0%) and in 95.3% of AIN 2/3 (95% CI: 84.2-99.4%). Among cancers, the highest prevalence was observed in warty-basaloid subtype
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Cancer
ISSN
0020-7136
e-ISSN
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Volume of the periodical
136
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
98-107
UT code for WoS article
000344011400011
EID of the result in the Scopus database
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