Frequency discrimination in rats exposed to noise as juveniles

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909446" target="_blank" >RIV/00216208:11120/15:43909446 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/15:00452448

Result on the web

<a href="http://dx.doi.org/10.1016/j.physbeh.2015.03.005" target="_blank" >http://dx.doi.org/10.1016/j.physbeh.2015.03.005</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.physbeh.2015.03.005" target="_blank" >10.1016/j.physbeh.2015.03.005</a>

Result language

angličtina

Original language name

Frequency discrimination in rats exposed to noise as juveniles

Original language description

Sound exposure during the early postnatal period can significantly influence the function of the auditory system in rats during adulthood. In the present study, rat pups (strain Long-Evans) were exposed to broad-band noise at 125 dB SPL for 8, 12 or 25 min on postnatal day 14 and then at the age of 3-5 months their frequency discrimination at 4 and 16 kHz was assessed using a modified method of the prepulse inhibition of the acoustic startle reflex. In all groups of exposed rats, an altered frequency discrimination of the tonal stimuli was observed, in comparison with controls, at 70 dB SPL. A worsening of frequency discrimination was observed even in animals exposed for 8 min, the auditory thresholds of which were almost identical to that of control animals. The individual auditory thresholds did not correlate with frequency discrimination. The difference in frequency discrimination between the exposed and control animals disappeared at 85-90 dB SPL. Our data suggests that brief noise

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiology &amp; Behavior

ISSN

0031-9384

e-ISSN

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Volume of the periodical

144

Issue of the periodical within the volume

May 15

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

60-65

UT code for WoS article

000353751900008

EID of the result in the Scopus database

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