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Development of the acoustic startle response in rats and its change after early acoustic trauma

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F71226401%3A_____%2F15%3A%231006180" target="_blank" >RIV/71226401:_____/15:#1006180 - isvavai.cz</a>

  • Alternative codes found

    RIV/68378041:_____/15:00452413 RIV/00216208:11120/15:43909447

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.bbr.2015.02.046" target="_blank" >http://dx.doi.org/10.1016/j.bbr.2015.02.046</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.bbr.2015.02.046" target="_blank" >10.1016/j.bbr.2015.02.046</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Development of the acoustic startle response in rats and its change after early acoustic trauma

  • Original language description

    Even brief acoustic trauma during the critical period of development that results in no permanent hearing threshold shift may lead to altered auditory processing in adulthood. By monitoring the acoustic startle response (ASR), we examined the developmentof auditory function in control rats and in rats exposed to intense noise at the 14th postnatal day (P14). First ASRs appeared on P10?P11 to intense low-frequency tones. By P14, the range of sound intensities and frequencies eliciting ASRs extended considerably, the ASR reactivity being similar at all frequencies (4?32 kHz). During the subsequent two weeks, ASR amplitudes to low-frequency stimuli (4?8 kHz) increased, whereas the ASRs to high-frequency tones were maintained (16 kHz) or even decreased (32 kHz). Compared to controls, noise exposure on P14 (125 dB SPL for 8, 12, or 25 min) produced transient hyper-reactivity to startle stimuli, manifested by a decrease of ASR thresholds and an increase of ASR amplitudes. ASR enhancement oc

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Behavioural Brain Research

  • ISSN

    0166-4328

  • e-ISSN

  • Volume of the periodical

    286

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    212-221

  • UT code for WoS article

    000353599600029

  • EID of the result in the Scopus database

    2-s2.0-84924714571