Late medical therapy of patent ductus arteriosus using intravenous paracetamol
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43910908" target="_blank" >RIV/00216208:11120/15:43910908 - isvavai.cz</a>
Alternative codes found
RIV/00023698:_____/15:N0000008
Result on the web
<a href="http://dx.doi.org/10.1136/archdischild-2014-307930" target="_blank" >http://dx.doi.org/10.1136/archdischild-2014-307930</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1136/archdischild-2014-307930" target="_blank" >10.1136/archdischild-2014-307930</a>
Alternative languages
Result language
angličtina
Original language name
Late medical therapy of patent ductus arteriosus using intravenous paracetamol
Original language description
Objective To investigate the effect of late treatment with intravenous paracetamol on patent ductus arteriosus (PDA) closure prior to possible PDA ligation. Methods A retrospective review of infants with a haemodynamically significant PDA, considered forPDA ligation and treated with intravenous paracetamol prior to possible ligation. Results Thirty six infants with a median gestation of 26.1 weeks received paracetamol at a median age of 27 days. Paracetamol was associated with immediate closure in nine(25%) infants. There was no response to paracetamol treatment in four (11%) infants who subsequently underwent a PDA ligation. In 23 (64%) infants, the PDA constricted and all but one of this group demonstrated complete PDA closure prior to discharge. Conclusions There may be a role for intravenous paracetamol in late closure of infants with a significant PDA to avoid ligation. The use of paracetamol for late treatment of PDA should be systematically evaluated.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FK - Gynaecology and obstetrics
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of Disease in Childhood: Fetal and Neonatal Edition
ISSN
1359-2998
e-ISSN
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Volume of the periodical
100
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
"F253"-"F256"
UT code for WoS article
000354143600015
EID of the result in the Scopus database
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