Complex approach to skin repair in an extensively burned child: a case study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920393" target="_blank" >RIV/00216208:11120/20:43920393 - isvavai.cz</a>

Alternative codes found

RIV/00064173:_____/20:N0000119

Result on the web

<a href="https://doi.org/10.12968/jowc.2020.29.8.458" target="_blank" >https://doi.org/10.12968/jowc.2020.29.8.458</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.12968/jowc.2020.29.8.458" target="_blank" >10.12968/jowc.2020.29.8.458</a>

Result language

angličtina

Original language name

Complex approach to skin repair in an extensively burned child: a case study

Original language description

The limited amount of donor sites and loss of dermis are major challenges in the therapy of extensively burned patients. Here, we present a complex treatment approach of an eight-year-old boy with full-thickness burns on 90% of the total body surface area, using simple and efficient techniques of tissue engineering. To obtain sufficient skin for grafting we repeatedly harvested the same anatomical areas. Acceleration of donor site healing was achieved by treatment with a suspension of noncultured autologous skin cells (NASC) and acellular porcine dermis (Xe-Derma (XD), Czech Republic). Moreover, such wound management allowed up to six reharvestings, compared with one-to-three procedures following routine treatment. Bilayer Integra template (Integra LifeSciences Corp., US) was used as the dermal substitute in over 60% of full-thickness burns. Following successful vascularisation of the neodermis in 3-4 weeks, the templates were covered with meshed split-thickness skin grafts (STSG), or Meek autografts, and facilitated by NASC/XD. We may conclude that such a &apos;sandwich&apos; technique approach, combining four biological covers (Integra, STSG, NASC and XD), significantly contributed to the successful skin repair of the patient.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30212 - Surgery

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Wound Care

ISSN

0969-0700

e-ISSN

—

Volume of the periodical

29

Issue of the periodical within the volume

8

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

458-463

UT code for WoS article

000562967200007

EID of the result in the Scopus database

2-s2.0-85089712041